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KMID : 0980720130320020205
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Keimyung Medical Journal
2013 Volume.32 No. 2 p.205 ~ p.208
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Rapidly Evolving Bilateral Ophthalmoplegia as an Initial Manifestation of Myasthenia
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Lee Chang-Yeob
Jeon Ji-Ye
Lee Byung-Chan
Lee Hyung
Lim Jeong-Geun
Kim Hyun-Ah
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Abstract
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Myathenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigue. Symptoms are caused by circulating antiboties that block acetylcholine receptor at the post synaptic neuromuscular juction, inhibiting the excitatory effects of the neurotransmitter acetylcholine on receptor. At early stage of myasthenia gravis, ptosis and diplopia are common symptoms. The ophthalmoplegia is a rare symptom of the early stage of myasthenia gravis. We described a 52-year-old female with myasthenia gravis, presenting with acute ophthalmoplegia. Within 3 weeks the patient was transferred to intensive care unit because of respiratory failure. Thus, we have to consider that acute ophthalmolegia can be the initial symptom of myasthenia gravis and disease course is rapidly deteriorated.
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KEYWORD
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Acute ophthalmoplegia, Myasthenia gravis
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